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MedDRA
Medical Dictionary for Regulatory Activities (new global standard medical terminology designed to supersede other terminologies (such as COSTART and ICD9) used in the medical product
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
PD
Pharmacodynamics. The effect of the drug on physiological measures in the subject.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
PK
Pharmacokinetics. The study of the absorption, distribution, metabolism and excretion of a drug.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
QD
Every Day (Latin: quaque die)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
SDS
Submission Data Standards. Also the name of the Team that created the SDTM and SDTMIG
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
SDTMIG
Submission Data Standards SDTM Implementation Guide for Human Clinical Trials (this document)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
SEND
Standard for Exchange of Non-Clinical Data
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
SF-36
A multi-purpose, short-form health survey with 36 questions
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
SNOMED
Systematized Nomenclature of Medicine (a dictionary)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
SOC
CDISC System Organ Class --BODSYS Populated using a code value in the list of controlled terms, codelist SOC (C66783) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
TID
Three Times Daily (Latin: ter in die)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
TMAX
The time after dosing when Cmax occurs (PK) or when the maximum effect is observed (PD)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
UUID
Universally Unique Identifier V3.x Version 3.1 of the SDSIG and all subsequent versions of the SDTMIG
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
WHODRUG
World Health Organization Drug Dictionary
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 274
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Treatment
--CAN Populated using a code value in the list of controlled terms, codelist ACN (C66767) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Age Unit
Populated using a code value from the list of controlled terms, codelist AGEU (C66781) at http://www.cdisc.org/standards/terminology/index.html Units are associated with
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
AESEV
Populated using a code value in the list of controlled terms, codelist AESEV (C66769) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
ETHNIC
Will be changed to Subject Ethnic Group in the future
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Form
--DOSFRM Populated using a code value in the list of controlled terms, codelist FRM (C66726) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Size
Controlled Terms for when VSTESTCD = FRMSIZE (Frame Size) Populated using a code value in the list of controlled terms, codelist SIZE (C66733) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
IECAT
Populated using a code value in the list of controlled terms, codelist IECAT (C66797) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
LBTESTCD
Populated using a code value in the list of controlled terms, codelist LBTESTCD (C65047) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
LBTEST
Populated using a code value in the list of controlled terms, codelist LBTEST (C65154) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
See also LBTESTCD
CDISC SDTM Implementation Guide (Version 3.1.2)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 276
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Non-Completion
DSDECOD when DSCAT = “DISPOSITION EVENT” Populated using a code value in the list of controlled terms, codelist NCOMPLT (C66727) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
No Yes Response
--PRESP, --OCCUR, --SCAN, --SCONG, --SDISAB, --SDTH, --SHOSP, --SLIFE, --SOD, --SMIE, --CONTRT, --BLFL, --FAST, --DRVFL, ADDON (Trial Summary Parameter) Populated using a code value in the list of controlled terms, codelist NY (C66742) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Outcome of Event
--OUT Populated using a code value in the list of controlled terms, codelist OUT (C66768) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
ROUTE
Route of Administration --ROUTE Populated using a code value in the list of controlled terms, codelist ROUTE (C66728) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
SEX
Populated using a code value in the list of controlled terms, codelist SEX (C66731) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
VSTESTCD
Populated using a code value in the list of controlled terms, codelist VSTESTCD (C66741) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
VSTEST
Populated using a code value in the list of controlled terms, codelist VSTEST (C67153) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
See also VSTESTCD
CDISC SDTM Implementation Guide (Version 3.1.2) CDISC, © 2007. All rights reserved
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Applicable
Added as a “restricted prefix” and variable naming prefix - see Appendix D. Do not use as a Domain Code. Included as a value in the list of controlled terms, codelist Domain Abbreviation (C66734) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Events
Evidence of disease or condition, including objective signs and subjective symptoms that are typically observed by a physician or described to the investigator by the subject.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Findings
Semi-Quantitative measurement of vertebral fractures CDISC SDTM Implementation Guide (Version 3.1.2)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Purpose
See SDTM 3.3. Included as a value in the list of controlled terms, codelist Domain Abbreviation (C66734) at http://www.cdisc.org/standards/terminology/index.html CDISC SDTM Implementation Guide (Version 3.1.2) CDISC, © 2007. All rights reserved
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 278
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Meal Data
Interventions Information regarding the subject's meal consumption, such as fluid intake, amounts, form (solid or liquid state), frequency, etc., typically used for PK analysis. Included as a value in the list of controlled terms, codelist Domain Abbreviation (C66734) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
will not be used with
SDTM standard domains, where - may be any valid letter or number. CDISC SDTM Implementation Guide (Version 3.1.2)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 280
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Autopsy
TBD (To Be Determined) Additional data about deaths, specific to findings from autopsies.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Under Discussion
Included as a value in the list of controlled terms, codelist Domain Abbreviation (C66734) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Under Development
Included as a value in the list of controlled terms, codelist Domain Abbreviation (C66734) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 282
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Treatments
Populated using a code value from the list of controlled terms, codelist No Yes Response (C66742) at http://www.cdisc.org/standards/terminology/index.html Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
DO NOT USE -
Information on dictionaries and dictionary versions be
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
included in the SDTM
metadata, since the define.xml specification has explicit mechanisms for handling references to dictionaries and dictionary versions. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
at
http://www.cdisc.org/standards/terminology/index.html CDISC SDTM Implementation Guide (Version 3.1.2) APPENDIX C4: DRUG ACCOUNTABILITY TEST CODES The following table contains the test codes suggested by CDISC for use in DRUG Accountability domains.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
of Subjects
No controlled terminology. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Age Group
Populated using a code value from the list of controlled terms, codelist AGESPAN (C66780) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
A record for each
applicable category should be included. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
AGEMAX
Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Name
No controlled terminology. In the future, may be added to list of controlled terms on CDISC website.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Administration
(ROUTE) Includes many more controlled terms than for those listed in CDISC Notes for – ROUTE. Includes more specific routes than INHALATION listed in CDISC notes for SUROUTE on page 50.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
to submit dosing
parameters, as the TE and TA datasets are better suited to describing such information. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Frequency
Use controlled terminology for interventions (DOSFRQ). Dose frequency associated with a test product or comparative treatment. In the future, may be added to list of controlled terms on CDISC website
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Dose Units
Use controlled terminology for interventions (DOSU). Units used with value(s) in DOSE. In the future, may be added to list of controlled terms on CDISC website
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Indication
No controlled terminology. In the future, may be added to list of controlled terms on CDISC website
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Trial Length
No controlled terminology. Defined as the planned
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
length of time for a
subject's participation. It should be recorded using
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
the IS8601 format for
durations, see Section 4.1.4.3. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 284
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Objective
No controlled terminology Should be described in
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
terms of the desired
statement in labeling. In the future, may be added to list of controlled terms on CDISC website
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Subjects
No controlled terminology. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Randomized
Populated using a code value from the list of controlled terms, codelist NY (C66742) at http://www.cdisc.org/standards/terminology/index.html Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Participants
Populated using a code value from the list of controlled terms, codelist SEXPOP (C66732) at http://www.cdisc.org/standards/terminology/index.html Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Organization
No controlled terminology. In the future, may be added to list of controlled terms on CDISC website
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Rules
If the trial has study stop rules (STOPRULE is not equal to "NONE"), contains a description of the stop rules. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Schema
Populated using a code value from the list of controlled terms, codelist TPLIND (C66735) at http://www.cdisc.org/standards/terminology/index.html Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Control Type
Populated using a code value from the list of controlled terms, codelist TCNTRL (C66785) at http://www.cdisc.org/standards/terminology/index.html Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Group
Populated using a code value from the list of controlled terms, codelist TDIGRP (C66787) at http://www.cdisc.org/standards/terminology/index.html If trial does not enroll healthy subjects (TDIGRP is not equal to "HEALTHY SUBJECTS"), contains the diagnosis of subjects to be enrolled. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Type
Populated using a code value from the list of controlled terms, codelist TINDTP (C66736) at http://www.cdisc.org/standards/terminology/index.html
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
TINDTP provides a
classification system for the indication provided as text in INDIC.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
the adverse effect of
another treatment. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Classification
Populated using a code value from the list of controlled terms, codelist TPHASE (C66737) at http://www.cdisc.org/standards/terminology/index.html The controlled terminology for phase includes several formats as synonyms. Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
of Test Product
No controlled terminology. In the future, may be added to list of controlled terms on CDISC website
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Trial Type
Populated using a code value from the list of controlled terms, codelist TTYPE (C66739) at http://www.cdisc.org/standards/terminology/index.html Included as a value in the list of controlled terms, codelist Trial Summary Parameter Test Code (C66738)
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Returned Amount
APPENDIX C5: SUPPLEMENTAL QUALIFIERS NAME CODES The following table contains an initial set of standard name codes for use in the Supplemental Qualifiers (SUPP--) special-purpose datasets. There are no specific conventions for naming QNAM and some sponsors may choose to include the 2- character domain in the QNAM variable name. Note that the 2-character domain code is not required in QNAM since it is present in the variable RDOMAIN in the SUPP-- datasets.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Dictionary Version
AE, MH, PE and other domains that use dictionary-
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
High Level Group Term
AE, MH, PE, and any other domain coded to MedDRA --HLT
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
High Level Term
AE, MH, PE, and any other domain coded to MedDRA --LLT
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Lower Level Term
AE, MH, PE, and any other domain coded to MedDRA
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
ITT
Intent to Treat Population Flag
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 286
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
RL
CDISC, © 2007. All rights reserved
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 288
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
General
Changed abbreviation from SDSIG to SDTMIG . Updated references to SDTM v1.1. Introduced abbreviation of V3.x to refer to V3.1 IG and subsequent versions.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Change
Controlled Terminology - Type of Trial (TTYPE) 1) TSPARMCD was changed from TYPE on page 170 to TTYPE. 2) TSVAL CONFIRMATORY and EXPLORATORY were removed based on review comments. 3) TSVAL PHARMACODYNAMICS changed to PHARMACODYNAMIC 4) TSVAL PHARMACOGENOMICS changed to PHARMACOGENOMIC TSVAL PHARMACOKINETICS changed to PHARMACOKINETIC
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Add
10.3.1 Added SI Infection Site Measurements to domain codes.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Document
New Pharmacokinetics Parameters domain model and example
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Correct
10.4 Corrected list of fragments (Domain codes are no longer included in this fragment list, but appear only in 10.3.1). E4: CHANGES FROM CDISC SDTMIG V3.1.1 TO V3.1.2 DRAFT Note: This is limited to Appendix 10 changes as of current printing.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Sections 5
& 6 Changed the header for all domain models to use lowercase xpt filenames for consistency with eCTD specifications.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Section 6
Changed domain models for CM, SU, AE, MH to address possible use of new SUPP-- variable --PRESP, reconsider use of --OCCUR, and emphasize importance of including data that represents actual interventions or events.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 290
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Page 292
CDISC. © 2007. All rights reserved July 25, 2007
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
move
6.1.1.0 Added new assumption 5 to discuss record structure. Removed old assumption 5 (which was redundant with Notes and Section 4.1.4.7.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null
Replace
9.5.1 Replaced Trial Design examples with new examples to better communicate core concepts; added new TS example.
[ "SDTM.pdf" ]
SDTM.pdf
pdf
glossary.json
null
null